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Jun Chen Selected Research

MicroRNAs (MicroRNA)

4/2024Dual miRNA-Triggered DNA Walker Assisted by APE1 for Specific Recognition of Tumor Cells.
2/2024A dual-signal amplification strategy based on rolling circle amplification and APE1-assisted amplification for highly sensitive and specific miRNA analysis for early diagnosis of alzheimer's disease.
1/2024Dual-Signal Amplification Strategy Based on Catalytic Hairpin Assembly and APE1-Assisted Amplification for High-Contrast miRNA Imaging in Living Cells.
10/2023Endogenous Enzyme-Powered DNA Nanomotor Operating in Living Cells for microRNA Imaging.
1/2023miR-126 promotes M1 to M2 macrophage phenotype switching via VEGFA and KLF4.
1/2023MiR-199a-5p-containing macrophage-derived extracellular vesicles inhibit SMARCA4 and alleviate atherosclerosis by reducing endothelial cell pyroptosis.
1/2023miR-1 Inhibits the Ferroptosis of Chondrocyte by Targeting CX43 and Alleviates Osteoarthritis Progression.
12/2022A domino-like localized cascade toehold assembly amplification-based DNA nanowire for microRNA imaging in living cells.
12/2022Light-Controlled Recruitable Hybridization Chain Reaction on Exosome Vehicles for Highly Sensitive MicroRNA Imaging in Living Cells.
6/2022miR-98-5p as a novel biomarker suppress liver fibrosis by targeting TGFβ receptor 1.
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Jun Chen Research Topics

Disease

638Neoplasms (Cancer)
05/2024 - 01/2002
156Inflammation (Inflammations)
05/2024 - 09/2002
123Lung Neoplasms (Lung Cancer)
04/2024 - 04/2004
103Pain (Aches)
04/2024 - 01/2002
99Infections
05/2024 - 09/2004
98Neoplasm Metastasis (Metastasis)
02/2024 - 05/2002
89Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
02/2024 - 02/2006
87Hepatocellular Carcinoma (Hepatoma)
05/2024 - 10/2003
59Stomach Neoplasms (Stomach Cancer)
03/2024 - 09/2005
59Carcinogenesis
02/2024 - 01/2006
58Ischemia
04/2024 - 01/2002
57Stroke (Strokes)
03/2024 - 06/2004
54COVID-19
04/2024 - 01/2020
52Brain Injuries (Brain Injury)
08/2022 - 01/2002
51Fibrosis (Cirrhosis)
11/2023 - 04/2006
49Brain Ischemia (Cerebral Ischemia)
01/2023 - 01/2002
43Body Weight (Weight, Body)
01/2024 - 08/2007
42Hypoxia (Hypoxemia)
02/2024 - 05/2002
42Breast Neoplasms (Breast Cancer)
01/2024 - 02/2002
40Carcinoma (Carcinomatosis)
04/2023 - 03/2002
39Adenocarcinoma of Lung
02/2024 - 04/2008
36Hypersensitivity (Allergy)
01/2023 - 11/2003
35Ischemic Stroke
03/2024 - 08/2007
33Wounds and Injuries (Trauma)
05/2024 - 01/2002
33Cardiovascular Diseases (Cardiovascular Disease)
01/2024 - 05/2005
32Prostatic Neoplasms (Prostate Cancer)
01/2023 - 05/2002
31Glioma (Gliomas)
01/2023 - 12/2010
30Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
07/2023 - 11/2003
28Colorectal Neoplasms (Colorectal Cancer)
03/2024 - 01/2009
28Infarction (Infarctions)
03/2024 - 06/2004
27Hyperalgesia
04/2023 - 04/2001
27Major Depressive Disorder (Major Depressive Disorders)
11/2022 - 08/2010
25Alzheimer Disease (Alzheimer's Disease)
02/2024 - 07/2003
25Hemorrhage
01/2024 - 12/2003
24Atherosclerosis
01/2024 - 03/2002
23Traumatic Brain Injuries (Traumatic Brain Injury)
03/2024 - 07/2002
22Myocardial Infarction
05/2024 - 11/2006
21Ovarian Neoplasms (Ovarian Cancer)
11/2023 - 03/2007
19Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2024 - 01/2012
19Necrosis
07/2023 - 10/2005
18Obesity
05/2024 - 02/2004
18Disease Progression
04/2024 - 04/2011
18Pneumonia (Pneumonitis)
04/2024 - 03/2014
18Adenocarcinoma
01/2024 - 09/2014
18Thrombosis (Thrombus)
12/2023 - 07/2008
18Sepsis (Septicemia)
11/2023 - 07/2011
18Pancreatic Neoplasms (Pancreatic Cancer)
10/2023 - 01/2011
17Tuberculosis (Tuberculoses)
04/2024 - 11/2007
17Insulin Resistance
04/2024 - 02/2009
17Parkinson Disease (Parkinson's Disease)
01/2024 - 07/2003
17Schizophrenia (Dementia Praecox)
01/2023 - 04/2009

Drug/Important Bio-Agent (IBA)

213Proteins (Proteins, Gene)FDA Link
05/2024 - 05/2002
141Biomarkers (Surrogate Marker)IBA
05/2024 - 12/2007
66MicroRNAs (MicroRNA)IBA
04/2024 - 05/2004
65CytokinesIBA
04/2024 - 12/2004
55DNA (Deoxyribonucleic Acid)IBA
04/2024 - 01/2002
53RNA (Ribonucleic Acid)IBA
05/2024 - 09/2006
49Peptides (Polypeptides)IBA
12/2023 - 07/2008
46Messenger RNA (mRNA)IBA
02/2024 - 08/2002
45EnzymesIBA
03/2024 - 03/2002
40Immune Checkpoint InhibitorsIBA
04/2024 - 01/2018
40Therapeutic UsesIBA
04/2024 - 12/2003
39Glucose (Dextrose)FDA LinkGeneric
01/2024 - 05/2002
39Bee Venoms (Bee Venom)IBA
01/2021 - 04/2001
38Long Noncoding RNAIBA
05/2024 - 03/2016
36Paclitaxel (Taxol)FDA LinkGeneric
11/2023 - 12/2003
34Small Interfering RNA (siRNA)IBA
03/2024 - 06/2003
30LigandsIBA
02/2024 - 06/2008
29ErbB Receptors (EGF Receptor)IBA
11/2023 - 12/2009
28Neuroprotective AgentsIBA
10/2023 - 07/2002
27LipidsIBA
05/2024 - 11/2007
26Doxorubicin (Adriamycin)FDA LinkGeneric
11/2023 - 02/2002
26AntigensIBA
04/2023 - 07/2004
25AntioxidantsIBA
02/2024 - 06/2002
24Phosphotransferases (Kinase)IBA
11/2023 - 09/2004
24Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2022 - 05/2003
23Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2024 - 08/2002
21VaccinesIBA
10/2023 - 07/2007
20Interleukin-6 (Interleukin 6)IBA
12/2024 - 12/2007
20Anti-Bacterial Agents (Antibiotics)IBA
04/2024 - 07/2004
20Reactive Oxygen Species (Oxygen Radicals)IBA
03/2024 - 01/2009
20SolutionsIBA
10/2023 - 12/2008
20Cisplatin (Platino)FDA LinkGeneric
01/2023 - 03/2002
19Oxygen (Dioxygen)IBA
02/2024 - 10/2003
19Tyrosine Kinase InhibitorsIBA
11/2023 - 12/2009
18Analgesics (Analgesic Drugs)IBA
01/2023 - 01/2002
17CollagenIBA
05/2024 - 03/2009
17Transcription Factors (Transcription Factor)IBA
01/2024 - 01/2014
17Caspase 3 (Caspase-3)IBA
10/2023 - 05/2002
16HydrogelsIBA
05/2024 - 01/2010

Therapy/Procedure

358Therapeutics
05/2024 - 08/2003
111Drug Therapy (Chemotherapy)
05/2024 - 06/2004
66Immunotherapy
05/2024 - 08/2011
33Radiotherapy
01/2024 - 06/2004
21Chinese Traditional Medicine (Traditional Chinese Medicine)
11/2023 - 11/2008
19Aftercare (After-Treatment)
02/2024 - 07/2004
19Gastrectomy
11/2023 - 03/2004
18Liver Transplantation
05/2024 - 08/2007
18Lasers (Laser)
01/2022 - 04/2009
17Stents
11/2022 - 05/2002